How To Give Prascend To Horses?

When it comes to giving Prascend to horses, it’s important to ensure proper administration for the well-being of the animal.

Prascend is commonly used to manage the symptoms of Equine Cushing’s disease, and it’s crucial to follow the recommended guidelines.

To give Prascend to horses, you can either mix the tablet with a small amount of food or administer it directly into the back of the horse’s mouth.

It’s essential to consult with a veterinarian for the right dosage and administration technique, as they can provide personalized guidance based on the horse’s specific needs.

By following the proper steps to give Prascend to horses, you can help manage their condition and improve their overall health and quality of life.

how to give prascend to horses

Understanding the Benefits of Prascend for Equine Health

Prascend is a medication that has revolutionized the treatment of equine health conditions, particularly in horses suffering from pituitary pars intermedia dysfunction (PPID), also known as Cushing’s disease. This article will delve into the various benefits of Prascend and how it aids in maintaining the overall well-being of horses.

1. Managing PPID Symptoms

One of the primary benefits of Prascend is its effectiveness in managing the symptoms associated with PPID in horses. PPID is a hormonal disorder commonly found in older horses, characterized by an overactive pituitary gland. Symptoms include weight loss, muscle loss, abnormal hair growth, excessive sweating, and increased thirst.

Prascend contains the active ingredient pergolide mesylate, which acts as a dopamine agonist to suppress the excessive hormone production in the pituitary gland. By regulating hormone levels, Prascend helps alleviate the symptoms of PPID, allowing horses to lead a more comfortable and active life.

2. Improving Quality of Life

Horses with PPID often experience a decline in their overall quality of life due to the debilitating symptoms of the condition. Prascend plays a crucial role in improving the quality of life for these equines by effectively managing the disease. It helps horses regain their strength, maintain a healthy weight, and experience a renewed sense of energy.

Additionally, Prascend helps regulate insulin levels in horses, which is particularly beneficial as PPID is often associated with insulin dysregulation. This helps prevent the development of secondary conditions such as laminitis, a painful and potentially debilitating hoof disease.

3. Long-Term Management

Prascend offers long-term management of PPID, allowing horses to lead a fulfilling life well into their senior years. By suppressing the excessive hormone production in the pituitary gland, Prascend helps slow down the progression of the disease and mitigates the risk of further complications.

Regular administration of Prascend as prescribed by a veterinarian is essential for effective long-term management of PPID. It is important to closely monitor the horse’s response to the medication and adjust the dosage if necessary to ensure optimal results.

4. Ease of Administration

Another notable benefit of Prascend is its ease of administration. The medication is available in tablet form, which can be easily crushed and mixed with food or administered directly into the horse’s mouth. This makes it convenient for horse owners to ensure their equines receive the necessary medication without added stress or difficulty.

5. Veterinary Guidance

It is important to emphasize that the administration of Prascend should always be done under the guidance of a qualified veterinarian. They will assess the horse’s condition, conduct necessary tests, and determine the appropriate dosage and treatment plan.

In summary, Prascend is a valuable medication for the management of PPID in horses. Its ability to effectively control hormone levels, improve quality of life, and provide long-term management makes it an essential treatment option for equines suffering from this condition. With proper veterinary guidance and regular administration, Prascend offers significant benefits to enhance equine health and well-being.

Potential Side Effects and Precautions When Giving Prascend to Horses

Prascend is a medication commonly used in the treatment of pituitary pars intermedia dysfunction (PPID), also known as Cushing’s disease, in horses. While Prascend can be an effective treatment option, it is important for horse owners and caretakers to be aware of the potential side effects and precautions associated with its use.

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Potential Side Effects

Although Prascend is generally well-tolerated by horses, there are some potential side effects that should be monitored for:

  1. Gastrointestinal Upset: Some horses may experience mild gastrointestinal upset, such as decreased appetite, diarrhea, or colic-like symptoms. It is important to observe your horse closely for any signs of digestive disturbances and consult your veterinarian if they persist or worsen.
  2. Laminitis: Laminitis, a potentially serious and painful condition affecting the hoof, has been reported in some horses receiving Prascend. Lameness, increased digital pulses, and heat in the hooves may indicate the onset of laminitis. If you notice any of these signs, it is crucial to contact your veterinarian immediately.
  3. Changes in Water Consumption: Prascend can increase a horse’s water intake, leading to increased urination. Monitoring your horse’s water consumption and ensuring access to fresh and clean water at all times is essential.
  4. Other Rare Side Effects: Although rare, some horses may experience other side effects such as lethargy, depression, or changes in behavior. If you notice any unusual or concerning symptoms, it is advisable to seek veterinary guidance.


When administering Prascend to horses, it is important to follow these precautions:

  1. Veterinary Guidance: Prascend should only be used under the guidance and supervision of a veterinarian who can accurately diagnose PPID and determine the appropriate dosage for your horse.
  2. Dosage Compliance: It is crucial to administer Prascend as prescribed by your veterinarian. Skipping doses or altering the dosage without veterinary approval can compromise the effectiveness of the treatment.
  3. Monitoring: Regular monitoring of your horse’s condition, including clinical signs and hormone levels, is essential to assess the response to Prascend therapy and adjust the dosage if needed.
  4. Interaction with Other Medications: Inform your veterinarian about any other medications or supplements your horse may be receiving, as they can potentially interact with Prascend. Your veterinarian can provide guidance on any necessary adjustments or precautions.
  5. Pregnant or Breeding Horses: Prascend should be used with caution in pregnant or breeding horses, as its safety and potential effects on fertility have not been specifically evaluated.


Prascend is a commonly used medication for the treatment of PPID in horses. While it can be effective, horse owners and caretakers should be aware of the potential side effects and take necessary precautions when administering this medication. Monitoring for gastrointestinal upset, laminitis, changes in water consumption, and rare side effects is important. Following veterinary guidance, maintaining dosage compliance, regular monitoring, considering potential medication interactions, and exercising caution in pregnant or breeding horses are essential for the safe and effective use of Prascend.

Tips for Successfully Administering Prascend to Horses

Administering medication to horses can often be a challenging task, especially when it comes to oral medications like Prascend. Prascend is a commonly prescribed medication for horses with pituitary pars intermedia dysfunction (PPID), also known as Cushing’s disease. To ensure the effective administration of Prascend to horses, here are some useful tips:

1. Follow the Veterinarian’s Instructions

Before administering Prascend to your horse, it is essential to consult with a veterinarian. The vet will provide you with specific instructions for dosage and duration of treatment based on the horse’s condition. It is crucial to follow these instructions carefully to ensure the medication is administered correctly.

2. Familiarize Yourself with the Medication

Take some time to familiarize yourself with Prascend and its packaging. Read the instructions, warnings, and precautions provided by the manufacturer. Understanding the medication will help you handle it safely and administer it correctly to your horse.

3. Proper Handling and Storage

Prascend should be stored in a cool, dry place away from direct sunlight and moisture. Follow the storage instructions provided by the manufacturer to maintain the medication’s effectiveness. Additionally, ensure that you handle the medication with clean hands or wear disposable gloves to prevent contamination.

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4. Create a Comfortable Environment

Creating a calm and comfortable environment for your horse during medication administration can make the process easier. Choose a quiet area away from distractions and other animals. Some horses may respond well to being tied or held by a trusted handler, while others may require gentle restraint.

5. Use Appropriate Equipment

When administering Prascend, it is crucial to use the appropriate equipment. A dosing syringe or oral medication dispenser can help accurately measure and administer the medication. Make sure the equipment is clean and free from any residue from previous medications.

6. Mixing with Feed

In some cases, horses may be resistant to taking medication orally. If your horse refuses to take Prascend directly, consider mixing it with a small amount of moistened feed. Ensure that the horse consumes the entire dosage to ensure efficacy. Monitor your horse during feeding to ensure they consume the medication.

7. Observe for Side Effects

After administering Prascend, it is essential to monitor your horse for any possible side effects. Common side effects may include anorexia, diarrhea, or changes in behavior. If you notice any concerning symptoms, consult your veterinarian immediately.

8. Maintain a Consistent Schedule

Consistency is key when administering Prascend to horses. It is essential to establish a routine and administer the medication at the same time each day. This helps maintain steady levels of the medication in the horse’s system, ensuring its effectiveness.

9. Regular Veterinary Check-ups

Regular veterinary check-ups are crucial when administering Prascend to horses. The vet can monitor the horse’s progress, make any necessary adjustments to the dosage, and address any concerns or complications that may arise during treatment.

In summary, successful administration of Prascend to horses requires following the veterinarian’s instructions, familiarizing yourself with the medication, proper handling and storage, creating a comfortable environment, using appropriate equipment, considering mixing with feed if necessary, observing for side effects, maintaining a consistent schedule, and scheduling regular veterinary check-ups. By following these tips, you can ensure the effective treatment of pituitary pars intermedia dysfunction in your horse.

Frequently Asked Questions About Giving Prascend to Horses

Prascend is a medication commonly prescribed to horses with a condition called Equine Cushing’s disease or Pituitary Pars Intermedia Dysfunction (PPID). It helps manage the symptoms associated with this condition and improves the quality of life for affected horses. If you have questions about giving Prascend to your horse, this FAQ guide will provide you with the answers you need.

1. What is Prascend?

Prascend is the brand name for the drug pergolide, which is a dopamine agonist. It works by stimulating dopamine receptors in the brain, which helps regulate the production of hormones that are affected by Equine Cushing’s disease. Prascend is available in tablet form and is administered orally to horses.

2. What is Equine Cushing’s disease?

Equine Cushing’s disease is a hormonal disorder that affects the pituitary gland in horses. It results in the overproduction of certain hormones, particularly cortisol. This condition is commonly seen in older horses and can lead to a variety of health problems, including weight loss, excessive drinking and urination, and a long, curly coat that doesn’t shed properly.

3. How does Prascend help horses with Equine Cushing’s disease?

Prascend helps manage Equine Cushing’s disease by reducing the overproduction of certain hormones in the pituitary gland. It helps alleviate the symptoms associated with the condition, such as excessive drinking and urination, weight loss, and abnormal hair growth. Prascend does not cure Equine Cushing’s disease, but it helps improve the horse’s quality of life.

4. How is Prascend administered to horses?

Prascend is administered orally to horses. The tablets are typically crushed and mixed with a small amount of food to ensure the horse consumes the full dose. It’s important to follow the dosage instructions provided by your veterinarian and give the medication at the same time every day for optimal results.

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5. Are there any side effects of Prascend?

While Prascend is generally well-tolerated by horses, some side effects may occur. These can include loss of appetite, lethargy, diarrhea, and laminitis. It’s important to monitor your horse closely while on Prascend and report any concerning symptoms to your veterinarian.

6. Can Prascend be used in pregnant or lactating mares?

The safety of using Prascend in pregnant or lactating mares has not been established. It’s best to consult with your veterinarian before administering Prascend to horses in these conditions to ensure the health and well-being of the mare and foal.

7. Can Prascend interact with other medications?

Prascend may interact with certain medications, including drugs that affect blood pressure or those metabolized by the liver. It’s important to inform your veterinarian about any other medications your horse is taking to avoid potential drug interactions.

8. Can Prascend be used in other animals?

Prascend is specifically formulated for use in horses and should not be used in other animals, including dogs or cats. It’s important to only give medications to the species they are intended for to ensure safety and effectiveness.

9. How long does it take for Prascend to start working?

Prascend may take several weeks to start working and show noticeable improvements in horses with Equine Cushing’s disease. The response to treatment may vary from horse to horse, and it’s important to follow the treatment plan outlined by your veterinarian.

10. Can Prascend be used long-term?

Prascend is often used as a long-term medication to manage Equine Cushing’s disease. It’s important to regularly monitor your horse’s condition and adjust the dosage if necessary. Your veterinarian will provide guidance on the appropriate duration of treatment for your horse.

11. What should I do if I miss a dose of Prascend?

If you accidentally miss a dose of Prascend, give it as soon as you remember. However, if it’s close to the time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for the missed one.

12. Can I stop giving Prascend once my horse’s symptoms improve?



How should I give Prascend to horses?

Prascend should be given orally to horses. The recommended dosage is one tablet per day, which can be administered directly into the horse’s mouth or crushed and mixed with a small amount of feed.

Can Prascend be given with food?

Yes, Prascend can be given with or without food. However, it is important to ensure that the horse consumes the entire dose to receive the full benefit of the medication.

Are there any special instructions for administering Prascend?

It is important to follow the dosage and administration instructions provided by your veterinarian. Additionally, Prascend tablets should not be split or crushed unless directed by your vet, as this may affect the efficacy of the medication.


In conclusion, administering Prascend to horses is an essential part of managing Equine Cushing’s Disease. By carefully following the recommended dosage and administration guidelines, horse owners can effectively manage the symptoms and improve the overall health of their horses. Additionally, regular veterinary check-ups and ongoing monitoring of the horse’s condition are crucial to ensure the medication’s effectiveness and make necessary adjustments. Properly managing Equine Cushing’s Disease with Prascend can greatly enhance the horse’s quality of life, alleviate discomfort, and prolong their active years. Putting your horse’s health first by providing them with this medication is a responsible and caring decision.